| 维胺酯治疗痤疮类皮肤病的临床观察 |
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| 引用本文： | 虞瑞尧.维胺酯治疗痤疮类皮肤病的临床观察[J].中国新药与临床杂志,1986(1). |
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| 作者姓名： | 虞瑞尧 |
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| 作者单位： | 中国人民解放军总医院皮肤科 北京 |
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| 摘 要： | <正> 维甲酸类(retinoids)在皮肤科临床上的应用,即在痤疮、银屑病、各种角化异常性皮肤病以及某些癌前或癌性疾病的治疗上,均取得了令人鼓舞的治疗效果。口服维甲酸类药物在皮肤科的应用,已有较详细的介绍。本文就国产维甲酸类衍生物维甲酯在痤疮类皮肤病中的疗效及其毒副作用作以下介绍。维胺酯的化学名称为N-(4-氧碳基苯基)维生素甲酰胺N-(ethoxycarbephenyl)-retinamide。分子式C_(29)H_(37)NO_3其化学结构式如下。
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| 关 键 词： | 维甲酸类 维胺酯 痤疮 颜面播散性粟粒狼疮 |
Retinamidoester for acne and related dermatoses:Clinical observation |
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| Yu Rui-Yao.Retinamidoester for acne and related dermatoses:Clinical observation[J].Chinese Journal of New Drugs and Clinical Remedies,1986(1). |
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| Authors: | Yu Rui-Yao |
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| Abstract: | This paper recommend a retinoid derivative and is initiated and retinamidoester for treating acne and manufectured in China. Its therapeutic related dermatoses. The drug in use is results and untoward effects were pres- ented and pharmacology and toxicology discussed. Acne treated totaled 274 cas, s. Oosage schedule was 1.2-2.0mg/ (kg.d)or 25mg tid for adults. 104 cases (38%) was cured, 97(35.4%) markedly improved, and 64 (23.4%) moderate'y improved with an overall effective rate of 96.7%. Side effects (including toxicones) sccurred in 11 .8% and laboratory aberrations in 3. 8%. Mechanism of the drug, itsintraindications, and combined treatment were discussed. |
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| Keywords: | Retinoids Retinamidoe-ster Acne Lupus miliaris disseminatus faciei |
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