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Pulmonary hyalinizing granuloma with laryngeal and subcutaneous involvement: report of a case successfully treated with glucocorticoids
Authors:Shinohara Takeshi  Kaneko Takeshi  Miyazawa Naoki  Nakatani Yukio  Nishiyama Harumi  Shoji Akira  Ishigatsubo Yoshiaki
Affiliation:First Department of Internal Medicine, Yokohama City University School of Medicine, Yokohama, Kanagawa.
Abstract:We report a case of pulmonary hyalinizing granuloma (PHG) with laryngeal and subcutaneous involvement. A 43-year-old man was admitted to our hospital for assessment of hoarseness. Cervical and chest computed tomography, respectively, revealed a laryngeal tumor and two pulmonary masses. Specimens obtained from the pulmonary masses were compatible with PHG. The histopathology of biopsy specimens from both the laryngeal tumor and a subcutaneous tumor resembled that of the resected lung masses. Although there is no established treatment for PHG, the laryngeal tumor was diminished and all other lesions disappeared with glucocorticoid treatment.
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