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Comparison of outcomes of hematopoietic stem cell transplantation without chemotherapy conditioning by using matched sibling and unrelated donors for treatment of severe combined immunodeficiency
Authors:Christopher C. Dvorak,Amel Hassan,Mary A. Slatter,Manfred Hö  nig,Arjan C. Lankester,Rebecca H. Buckley,Michael A. Pulsipher,Jeffrey H. Davis,Tayfun Gü  ngö  r,Melissa Gabriel,Jacob H. Bleesing,Nancy Bunin,Petr Sedlacek,James A. Connelly,David F. Crawford,Luigi D. Notarangelo,Sung-Yun Pai,Jake Hassid,Paul Veys,Andrew R. Gennery,Morton J. Cowan
Affiliation:1. Division of Pediatric Allergy, Immunology, and Blood and Marrow Transplant, Benioff Children''s Hospital, University of California San Francisco, San Francisco, Calif;2. Centre for Immunodeficiency, Molecular Immunology Unit, UCL Institute of Child Health, London, United Kingdom;3. Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom;4. Department of Pediatrics, University Medical Center, Ulm, Germany;5. Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands;6. Departments of Pediatrics and Immunology, Duke University Medical Center, Durham, NC;g Division of Hematology and Hematologic Malignancies, Primary Children''s Hospital, University of Utah School of Medicine/Huntsman Cancer Institute, Salt Lake City, Utah;h Hematology/Oncology/BMT Program, British Columbia Children''s Hospital, Vancouver, British Columbia, Canada;i University Children''s Hospital, Stem Cell Transplantation Department, Zurich, Switzerland;j Oncology Department, The Children''s Hospital at Westmead, Westmead, Australia;k Department of Pediatrics, Cincinnati Children''s Hospital Medical Center, Cincinnati, Ohio;l Division of Oncology, Department of Pediatrics, Children''s Hospital of Philadelphia, Philadelphia, Pa;m Department of Pediatric Hematology and Oncology, Teaching Hospital Motol, Prague, Czech Republic;n Division of Pediatric Hematology-Oncology, University of Michigan, Ann Arbor, Mich;o Department of Pediatrics, University of Oklahoma, Oklahoma City, Okla;p Division of Immunology and The Manton Center for Orphan Disease Research, Children''s Hospital Boston, Harvard Medical School, Boston, Mass;q Division of Hematology and Oncology, Boston Children''s Hospital, and the Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Mass
Abstract:
Keywords:Severe combined immunodeficiency   hematopoietic cell transplantation   sibling donors   unrelated donors   umbilical cord blood   conditioning   serotherapy
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