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Causes of epidermal filaggrin reduction and their role in the pathogenesis of atopic dermatitis
Authors:Jacob P. Thyssen  Sanja Kezic
Affiliation:1. National Allergy Research Centre, Department of Dermato-Allergology, Copenhagen University Hospital Gentofte, University of Copenhagen, Hellerup, Denmark;2. Coronel Institute of Occupational Health, Academic Medical Center, Amsterdam, The Netherlands
Abstract:
Keywords:Atopic dermatitis   barrier function   filaggrin   histidine   ichthyosis vulgaris   lamellar body   pathogenesis   stratum corneum   TH2 cytokines   urocanic acid
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