| 力竭性游泳对小鼠脑、肝、肌组织自由基代谢和血清CK、LDH活性的影响 |
| |
| 引用本文： | 张蕴琨,焦颖,郑书勤,高峡,冯炜权. 力竭性游泳对小鼠脑、肝、肌组织自由基代谢和血清CK、LDH活性的影响[J]. 中国运动医学杂志, 1995, 0(2) |
| |
| 作者姓名： | 张蕴琨 焦颖 郑书勤 高峡 冯炜权 |
| |
| 作者单位： | 南京体育学院，国家体委运动医学研究所，北京体育大学 |
| |
| 摘 要： | 本文研究力竭性游泳对小鼠脑、肝、肌组织过氧化脂质（ＬＰＯ）、超氧化物歧化酶（ＳＯＤ）水平以及血清肌酸激酶（ＣＫ）、乳酸脱氢酶（ＬＤＨ）活性的影响。结果表明：力竭性游泳后小鼠肌组织自由基生成增多，ＬＰＯ水平显著增加，导致肌细胞膜通透性改变，血清ＣＫ、ＬＤＨ活性明显升高，同一运动负荷对小鼠不同组织器官自由基代谢的影响不尽相同，以骨骼肌变化最为明显，肝脏次之，脑组织变化相对稳定。
|
| 关 键 词： | 力竭性游泳，过氧化脂质，超氧化物歧化酶，肌酸激酶，乳酸脱氢酶 |
The Effects of Exhaustive Swimming on the Free Radical Metabolism and serum CK,LDH Activity in Rats |
| |
| Zhang Yunkun,et al. The Effects of Exhaustive Swimming on the Free Radical Metabolism and serum CK,LDH Activity in Rats[J]. Chinese Journal of Sports Medicine, 1995, 0(2) |
| |
| Authors: | Zhang Yunkun et al |
| |
| Affiliation: | Nanjing Institute of Physical Education |
| |
| Abstract: | Sixteen rats were randomly divided into 2 groups. The rats of the experimental group were killed immediately after exhaustive swimming following 12 day's swimming training.The malondialdehyde(MDA)and superoxide dismutase(SOD)in brain,liver and skeletal muscle,and creatine kinase(CK),lactate dehydrogenase(LDH)in skeletal muscle and serum were determined.The results showed that the MDA content of rats'skeletal muscle significantly elevated after exhaustive swimming(p<0.05).Serum CK and LDH activity increased(p<0.05),The MDA and SOD in brain didn't change.The MDA of liver had a trend of increasing.The results indicated that exhaustive exercise would lead to an increased free radical generation.The high level of lipid peroxidation increased the permeability of cell membrane in skeletal musele.The effects of exhaustive exercise on free radical metabolism were different in various organs. |
| |
| Keywords: | free radical lipid peroxidation superoxide dismutase creatine kinase lactate dehydrogenase. |
| 本文献已被 CNKI 等数据库收录！ |
