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中药乳痛安片的镇痛抗炎作用研究
引用本文:谢文利,朱江,晋玉章,宋宏良,黄宗堂. 中药乳痛安片的镇痛抗炎作用研究[J]. 时珍国医国药, 2009, 20(7)
作者姓名:谢文利  朱江  晋玉章  宋宏良  黄宗堂
作者单位:1. 中国人民武装警察部队医学院,天津,300162
2. 天津市医学科学研究所,300041
3. 天津百若克医药生物技术有限责任公司,天津,300300
摘    要:目的 观察中药乳痛安片的镇痛、抗炎作用.方法 采用甩尾法和小鼠扭体法观察乳痛安片镇痛作用;采用小鼠耳廓肿胀法、足肿胀法观察乳痛安片的抗炎作用.结果 乳痛安片能明显延长小鼠甩尾的潜伏期,同时使小鼠扭体反应次数明显减少(P<0.01);中、高剂量乳痛安片可使小鼠耳廓肿胀度明显减小(P<0.05),同时足肿胀度也明显减小(P<0.01).结论 乳痛安片具有明显的镇痛、抗炎作用.

关 键 词:乳痛安片  镇痛作用  抗炎作用

Study on Anti-inflammatory and Analgesic Effects of Rutongan Tablets in Animals
XIE Wen-li,ZHU Jiang,JIN Yu-zhang,SONG Hong-liang,HUANG Zong-tang. Study on Anti-inflammatory and Analgesic Effects of Rutongan Tablets in Animals[J]. Lishizhen Medicine and Materia Medica Research, 2009, 20(7)
Authors:XIE Wen-li  ZHU Jiang  JIN Yu-zhang  SONG Hong-liang  HUANG Zong-tang
Abstract:Objective To study the anti-inflammatory and analgesic effects of Rutongon tablets.Methods Study the analgesic effects of Rutongan tablets by tail flick and wringing test in mice;Study the anti-inflammatory effects of Rutongan tablets by foot-plate swelling test.Results Rutongan tablets could remarkably increase the tail flick latency period in mice (P<0.01),inhibit acetic acid -induced wringing reaction (P<0.01).Meanwhile Rutongan tablets reduced the auricula swelling in mice(P<0.05) and foot-plate swelling in rats (P<0.01).Conclusion Rutongan tablets possesses anti-inflammatory and analgesic effects.
Keywords:Rutongan tablats Anti-inflammatory effect  Analgesic effect
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