Evaluation of appropriate usage of fresh frozen plasma: Results of a regional audit in Iran |
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| Authors: | N Mirzamani A Molana E Poorani |
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| Institution: | 1. Golestan Blood Transfusion Organization, Gorgan, Golestan, Iran;2. Iran Blood Transfusion Organization, Research Center, Tehran, Iran;1. Department of Radiology, Guangdong Academy of Medical Sciences/Guangdong General Hospital,No. 106 Zhongshan Er Road, 510080, Guangzhou, China;2. Southern Medical University Graduate School,No. 1023-1063 ShatainanRoad, 510515, Guangzhou, China;1. Department of Surgery, University of Michigan Hospital, Ann Arbor, MI;2. Department of Radiology, Section of Neuroradiology, University of Michigan Hospital, Ann Arbor, MI;3. Department of Cardiothoracic Surgery, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, China;4. Department of Surgical Critical Care, Beijing Hospital Ministry of Health, Beijing, China;5. Department of Emergency Medicine, Flevoziekenhuis Hospital, Almere, The Netherlands;6. Department of Anesthesiology, VU University Medical Center, Institute for Cardiovascular Research, Amsterdam, The Netherlands;1. Haseki Training and Research Hospital, Department of Neurology, Istanbul, Turkey;2. Bezmialem Vakif University, Department of Otolaryngology-Head-Neck Surgery, Istanbul, Turkey;3. Ordu University, Department of Neurology, Cumhuriyet Yerle?kesi, PK 52200 Merkez, Ordu, Turkey;4. Kafkas University, Department of Neurology, Kars, Turkey;5. Haydarpa?a Training and Research Hospital, Department of Otolaryngology-Head-Neck Surgery, Istanbul, Turkey;6. Haseki Training and Research Hospital, Department of Radiology, Istanbul, Turkey;1. Assistant Professor, Department of Pathology, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha 442002, India;2. Professor and Head, Department of Pathology, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha 442002, India;1. Department of Surgical Gastroenterology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark;2. Institute for Inflammation Research, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark;3. Department of Surgery, University of Michigan, Ann Arbor, MI |
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| Abstract: | BackgroundFresh frozen plasma (FFP) is a major source of coagulation factor replacement therapy for patients with clotting factor deficiency. Although FFP is readily available for use in clinical practice its administration isn’t without risk. Studies on the use of FFP reveal that it is often overused or inappropriately used. We undertook an audit to assess the appropriateness of FFP transfusion in Gorgan’s hospitals.MethodsThis was a retrospective, audit done at 5 hospitals in Gorgan city regarding the use of 1592 units of FFP issued to 346 patients from March 2006 to March 2007. The appropriateness of FFP transfusion was analyzed according to British Council for Standardization in Hematology (BCSH) Guidelines 2004.ResultsIn this audit we identified a high rate of inappropriate FFP usage (53% of transfusion episodes). Most ‘Inappropriate’ FFP usage occurred when there was active bleeding, with normal (or unmeasured) coagulation tests (30% of transfusion episodes). In only 66% of FFP-transfused patients were coagulation variable measured at any point in the hospital episode.ConclusionInappropriate usage of FFP is often seen in medical facility and the right solution is needed to curb the misuse of this component. Regular utilization audit can identify correctable errors in transfusion practices. Formal education programs and existing information on FFP use should be directed to professionals ordering FFP. |
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