2008年成都地区40～79岁常住人群糖代谢异常患病率调查

目的 了解成都地区糖代谢异常的流行情况.方法 2008年4月至11月应用分层整群抽样方法,选取成都市3个大社区的40～79岁居民,给予口服葡萄糖耐量实验,进行问卷调查和体格检查.危险因素分析用非条件Logistic回归分析.结果 调查总人数为5205人,糖尿病患病率为18.0%(936/5205),其中既往有糖尿病史者为40.6%(380/936),未诊断的糖尿病患者为59.4%(556/936).空腹血糖受损、糖耐量受损和糖调节受损的患病率分别为2.5%(128/5205)、20.1%(1048/5205)和22.6%(1176/5205).空腹血糖受损、糖耐量受损、糖调节受损和糖尿病患病率性别间比较差异无统计学意义(X~2分别为2.156、1.689、0.320、0.115,均P＞0.05);糖耐量受损、糖调节受损和糖尿病的患病率随着年龄的增长而增加(X~2值分别为105.0、107.0、258.0,均P＜0.05);但空腹血糖受损的患病率与年龄无明显相关性(X~2=1.9,P＞0.05).而男性,城市人口,体质量、舒张压、甘油三酯和尿酸升高为糖调节受损的危险因素.腰围增大,甘油三酯、总胆固醇升高、高密度脂蛋白胆固醇降低为成都市40岁以上人群糖尿病的危险因素.结论 成都地区中老年人群糖代谢异常患病率高,有一半以上为新发糖尿病.糖调节受损和糖尿病的患病率均随年龄增长而增加.

Prevalence of the glycometabolic abnormality among resident people aged 40-79 years old in Chengdu area

Objective To estimate the prevalence of glycometabolic abnormality among adults aged 40-79 years in Chengdu area in 2008.Methods A cross-sectional population survey for glycometabolic abnormality using randomly cluster-sampling was performed from April to November in 2008,questionaire and 75 gram oral glucose tolerance test(OGTF)were conducted in 5205 subjects.Results Prevalence of diabetes mellitus,impaired fasting glucose(IFG),impaired glucose tolerance(IGT)and impaired glucose regulation(IGR)were 18.0%,2.5%,20.1% and 22.6%,respectively.The prevalence of glycometabolic abnormality have no differences between sexes.The prevalence of diabetes and IGT increased with aging,but the prevalence of IFG have no obvious associated with age.Male,urban population,obesity,increase of diastolic blood pressure,TG and UA are risk factors for IGR.Increase of waist circumference,TG,TC,and decreasd of HDL-C are risk factors for diabetes in more than 40 year-old population of Chengdu area.Conclusions Our results showed that the glycometabolic abnormality are highly prevalent in Chengdu residents;over half of them are undiagnosed diabetes.The prevalence of diabetes increased with aging.