狂犬疫苗接种五针免疫程序与2-1-1四针免疫程序的对比观察

目的了解狂犬疫苗2-1-1四针免疫程序的不良反应、血清抗体阳转率以及患者的依从性,为其在临床的推广应用提供数据支持。方法将856名犬伤门诊患者按照就诊时间随机分为两组,对照组患者给予传统五针程序免疫,实验组患者给予2-1-1四针程序免疫。随访、监测两组患者的抗体阳转率、不良反应发生率以及免疫依从性。结果两组患者不良反应发生率以及全程接种30d后血清抗体阳转率差异无统计学意义,(P>0.05),接受2-1-1四针程序患者的免疫依从性明显高于传统五针程序的患者,差异有统计学意义(P<0.05)。结论狂犬疫苗2-1-1四针免疫程序安全、经济、简便,患者依从性好,值得推广和普及。

The com-parative observation of wild dog vaccine immune progrm and five needle 2-1-1 four needles of immunization programs

Objective Understand wild dog vaccine to the 2-1-1 four needles immune program adverse reactions, serum antibodies Positive conversion rate and patient compliance. Methods 856 cases dog injury clinic patients according to clinical time randomly divided into two groups. Follow-up, monitoring two sets of patients antibody Positive conversion bad reaction rate, the incidence and immune compliance. Results The 2-1-1 four needles program patients’ immune compliance was obviously higher than that of the traditional five needle program patients （P 0.05）. Conclusion Rabies vaccine immunization program 2-1-1 four needle safe, economic, patient compliance is good, worthy of promotion and popularization.