| Abstract: | Summary Experiments on 1474 white mice showed that the addition of live or killed cells of the BCG vaccine to antigens from Gram-negative bacteria (B. coli, Breslau bacilli, and typhoid bacilli) considerably increased the effectiveness of immunization both of animals irradiated with 300 r, and of nonirradiated animals.The inoculations were made 24 hours after irradiation. The stimulating effect of the BCG vaccine was also marked when the two immunizations were made separately; in this case the BCG vaccine was given first, and the other vaccine 3–10 days later.As a result of the combined immunization, not only did more of the animals infected with living bacteria survive, but, in addition, antibody formation was augmented.(Presented by Active Member AMN SSSR, N. N. Zhukov-Verezhnikov) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 54, No. 9, pp. 78–81, September, 1962 |
