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Pseudomesotheliomatous lung cancer mimicking mesothelioma on 18F-FDG PET/CT images: report of 2 cases
Authors:Takatoshi Nakamori  Shigeru Kosuda  Yukishige Kyoto  Akira Fujikawa  Yutaka Naoi  Yoshitaka Nakamori
Institution:1. Department of Radiology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama, 359-8513, Japan
2. Department of Radiology, National Self-Defense Force Central Hospital, Tokyo, Japan
3. Department of Internal Medicine, Mishuku Hospital, Tokyo, Japan
Abstract:The authors report two cases of pseudomesotheliomatous lung cancer (PLC) detected by 18F-FDG PET/CT scan. 18F-FDG PET/CT clearly revealed the extent of the disease in both cases, a case of adenocarcinoma of the lung and a case of squamous cell carcinoma of the lung. Intense 18F-FDG uptake by the diffusely thickened pleurae and primary lesion was observed in both cases, and increased 18F-FDG uptake by a pelvic bone metastasis was observed in the case of squamous cell carcinoma. Although PLC is indistinguishable from malignant pleural mesothelioma on 18F-FDG PET/CT scans, 18F-FDG PET/CT was helpful in identifying the primary focus of the PLCs and in staging the disease. Diagnostic image interpreters should be familiar with the 18F-FDG PET/CT findings in PLC.
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