维生素D和维生素D缺乏性佝偻病的研究

进入21世纪,维生素D缺乏性佝偻病又出现了上升趋势.该文探讨了其病因:纯母乳喂养时间过长而未添加维生素D,尤其是那些摄入母亲自身是维生素D缺乏者乳汁的婴儿;由于各种原因造成婴儿日照时间减少,从而使得婴儿体内由皮肤转化的内源性维生素D的量大大减少;在很多温带地区移民人群中佝偻病的高发病率.因此,维生素D缺乏可能是一项国际妇幼保健问题,需再次强调对儿童及孕妇额外补充维生素D及日照的重要性.

Progress in study on vitamin D deficiency and vitamin D-deficient rickets

In the 21st century,there is an increasing tendency in prevalence of vitamin D-deficient rickets.In this article,we explored the etiology of the disease: prolonged periods of exclusive breastfeeding without vitamin D supplementation,particularly for those exclusive breastfed babies whose mothers are also vitamin D deficient;reduced opportunities for sunshine,resulting in decreased production of endogenous vitamin D converted in the skin;and the high prevalence of rickets in immigrant groups in many temperate zones.So,vitamin D deficiency may be an international maternal and child health problem.The importance of extra dietary vitamin D supplementation and sunshine should be re-emphasized for both children and pregnant women.