| 新驴胶补血颗粒对小鼠非特异性免疫、耐疲劳、耐缺氧功能的影响 |
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| 引用本文： | 谢安,谷陟欣,邹志,卢捷.新驴胶补血颗粒对小鼠非特异性免疫、耐疲劳、耐缺氧功能的影响[J].中南药学,2011,9(11):827-829. |
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| 作者姓名： | 谢安 谷陟欣 邹志 卢捷 |
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| 作者单位： | 九芝堂股份有限公司,长沙410007;湖南省中药固体制剂工程技术研究中心,长沙410007 |
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| 摘 要： | 目的观察新驴胶补血颗粒对正常小鼠单核巨噬细胞系统吞噬功能、耐疲劳、耐缺氧功能的影响。方法 采用碳粒廓清率法测定免疫功能;常压缺氧和常温游泳法测定耐缺氧和耐疲劳能力。结果新驴胶补血颗粒3g.kg-1组能提高小鼠单核巨噬细胞系统的吞噬指数(P<0.05),延长小鼠游泳时间和乏氧生存时间。结论新驴胶补血颗粒可以提高小鼠的非特异性免疫功能,耐疲劳以及耐缺氧功能。
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| 关 键 词： | 新驴胶补血颗粒 非特异性免疫 耐疲劳 耐缺氧 |
Effect of new Lvjiao Buxue Keli on non-specific immunity, anti-fatigue, and anti-anoxia function in mice |
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| XIE An,GU Zhi-xin,ZOU Zhi,LU Jie.Effect of new Lvjiao Buxue Keli on non-specific immunity, anti-fatigue, and anti-anoxia function in mice[J].Central South Pharmacy,2011,9(11):827-829. |
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| Authors: | XIE An GU Zhi-xin ZOU Zhi LU Jie |
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| Institution: | XIE An1,2,GU Zhi-xin1,ZOU Zhi1,LU Jie1,2*(1.Jiuzhitang Co.,Ltd,Changsha 410007,2.Research Center of Traditional Chinese Medicine Solid Preparation and Engineering Technology of Hunan,Changsha 410007) |
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| Abstract: | Objective To observe the effect of new Lvjiao Buxue Keli on the phagocytosis of mononuclear phagocyte system, anti-fatigue and antianoxia function in mice. Methods Carbon expurgation method was used to determine the immune function. Fatigue and acute anoxia in mice were produced by swimming and hypoxia under normal pressure and the survival time was determined. Results The new Lvjiao Buxue Keli of 3 g · kg^-1 group apparently elevated the index of phagocytosis of mononuclear phagocyte system （P〈0.05）, prolonged the survival time under hypoxia （P〈 0.01） and the swimming time （P〈0.05）. Conclusion The new Lvjiao Buxue Keli can improve the non-specific immunity, anti-fatigue and antianoxia function in mice. |
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| Keywords: | new Lvjiao Buxue Keli non-specific immunity anti-fatigue anti-anoxia |
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