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多囊卵巢综合征的胰岛素抵抗机制研究进展
引用本文:范乐平,朱杰.多囊卵巢综合征的胰岛素抵抗机制研究进展[J].医学综述,2009,15(9):1381-1383.
作者姓名:范乐平  朱杰
作者单位:天津市人民医院内分泌科,天津,300121
摘    要:多囊卵巢综合征(PCOS)是育龄妇女常见的内分泌失调性疾病,以月经紊乱、持续排卵障碍、雄激素分泌过多、卵巢多囊样等为特征。国外研究显示,PCOS患者胰岛素抵抗发生率为50%~70%,提示IR在PCOS的发病中扮演了重要角色。本文就多囊卵巢综合征患者胰岛素抵抗的特点、发病机制及治疗进展进行综述。

关 键 词:多囊卵巢综合征  胰岛素抵抗  高胰岛素血症  脂联素

Progress in Research on Insulin Resistance of Polycystic Ovary Syndrome
FAN Le-ping,ZHU Jie.Progress in Research on Insulin Resistance of Polycystic Ovary Syndrome[J].Medical Recapitulate,2009,15(9):1381-1383.
Authors:FAN Le-ping  ZHU Jie
Institution:. ( Department of Endocrinology, Tianjin People's Hospital, Tianjin 300121 , China)
Abstract:Polycystic ovarian syndrome(PCOS) ,a common endocrine disorder,is characterized by menstrual disorder,persistent anovulation,hyperandrogenism and ovarypolycystion etc. Insulin resistance (IR)is associated with 50% - 70% PCOS patients in foreign research, Insulin resistance appear to underlie many of the endocrine features of PCOS in a large proportion of such patients. The features of Insulin resistance, mechanism and advance in treatment of PCOS are reviewed in this article.
Keywords:Polycystic ovarian syndrome  Insulin resistance  Hyperinsulinemia  Adiponectin
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