| 视网膜疾病药物研究进展 |
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| 引用本文： | 钱仪敏,路文,王若男,李华. 视网膜疾病药物研究进展[J]. 中国新药杂志, 2020, 0(9): 1001-1006 |
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| 作者姓名： | 钱仪敏 路文 王若男 李华 |
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| 作者单位： | 中国医药工业研究总院 |
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| 基金项目： | 国家“重大新药创制”科技重大专项资助项目(2018ZX09201017-008)。 |
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| 摘 要： | 视网膜疾病是常见的致盲性眼病之一,其发病机制复杂,对视功能损伤大。常见的视网膜疾病有年龄相关性黄斑变性、糖尿病性视网膜病变、视网膜静脉阻塞等。目前视网膜疾病治疗分为非药物治疗和药物治疗,药物包括抗氧化剂、抗炎剂、视循环调节剂、细胞治疗产品、抗血管内皮生长因子(VEGF)药物等,其中抗VEGF药物发展较好。
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| 关 键 词： | 视网膜疾病 药物研究 抗VEGF药物 |
Advances in drug research for retinal diseases |
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| QIAN Yi-min,LU Wen,WANG Ruo-nan,LI Hua. Advances in drug research for retinal diseases[J]. Chinese Journal of New Drugs, 2020, 0(9): 1001-1006 |
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| Authors: | QIAN Yi-min LU Wen WANG Ruo-nan LI Hua |
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| Affiliation: | (China State Institute of Pharmaceutical Industry,Shanghai InnoStar Biotech Co.,Ltd.,Shanghai 201203,China) |
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| Abstract: | Retinal disease,which causes server visual impairment,is one of the common blinding eye diseases with complicated pathogenesis.Common retinal diseases include age-related macular degeneration,diabetic retinopathy,retinal vein occlusion,etc.Currently,the treatment of retinal diseases can be divided into non-drug treatment and drug treatment,including antioxidants,anti-inflammatory agents,visual circulation modulators,cell therapy products,anti-VEGF drugs and enterotrophin,among which anti-VEGF drugs are relatively well developed. |
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| Keywords: | retinal diseases drug research anti-VEGF drugs |
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