Synthesis and antitumor activity of pyrano[4′,3′:4,5]pyrido[2,3-b]thieno[3,2-d]-1,2,3-triazine and l,2,3-triazino[4′,5′:4,5¦thieno-[2,3-c]isoquinoline derivatives |
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| Authors: | E. G. Paronikyan A. S. Noravyan Sh. F. Akopyan F. G. Arsenyan G. M. Stepanyan B. T. Garibdzhanyan |
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| Affiliation: | (1) Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of Armenia, Yerevan, Armenia |
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| Abstract: | Methods for the synthesis of new heterosystems of condensed thieno[3,2-d]-1,2,3-triazines on the basis of pyrido[2,3-b]thiophenes have been developed. The antitumor activity of the synthesized compounds was studied and several compounds possessing low toxicity and moderate antitumor activity were found. __________ Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 40, No. 6, pp. 3–5, June, 2006. |
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