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眼底横向显微成像系统的研制及应用
引用本文:张运海,钮赛赛,朱冀梁,贾砚文. 眼底横向显微成像系统的研制及应用[J]. 中国医疗器械杂志, 2011, 35(1): 24-27. DOI: 10.3969/j.isnn.1671-7104.2011.01.006
作者姓名:张运海  钮赛赛  朱冀梁  贾砚文
作者单位:1. 苏州六六视觉科技股份有限公司,江苏,苏州,215005
2. 南京航空航天大学,机电学院,江苏,南京,210016
3. 南通大学附属医院眼科,江苏,南通,226001
基金项目:国家"十一五"863计划重点项目
摘    要:介绍了一套基于MEMS薄膜变形镜的人眼眼底横向显微成像系统。采用37单元MEMS薄膜变形反射镜作为波前校正元件,127微透镜阵列哈特曼夏克(Hartmann—Shack)波前传感器测量波前误差,在用计算机控制薄膜变形镜实现波前误差校正后,开启成像照明光源.用CCD相机记录视网膜图像。模拟眼试验表明.系统能够有效进行像差测量、校正和眼底成像,像差校正后成像质量达到衍射极限。临床试用表明,除少部分眼内比较浑浊的病人外,整个检查过程大部分病人都能够安全、快捷、可靠地进行。

关 键 词:微机电系统  眼底  显微成像

Development and Application of a Fundus Transverse Microscopic Imaging System
Zhang Yunhai,Niu Saisai,Zhu Jiliang,Jia Yanwen. Development and Application of a Fundus Transverse Microscopic Imaging System[J]. Chinese journal of medical instrumentation, 2011, 35(1): 24-27. DOI: 10.3969/j.isnn.1671-7104.2011.01.006
Authors:Zhang Yunhai  Niu Saisai  Zhu Jiliang  Jia Yanwen
Affiliation:1.66 VISION-TECH CO., LTD. 34Daru lane, Suzhou, 215005, China ;2 College of Mechanical & Electrical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016, China ;3 Department of Ophthalmology, Affiliated hospital of Nantong University, Nantong, 226001, China)
Abstract:A human fundus transverse microscopic imaging system based on a MEMS deformable membrane mirror was developed. A 37 element small MEMS deformable membrane mirror was used as wave front corrector in this system. Wavefront errors were measured by a Hartman-Shack wave front sensor which contains 127 micro lens lets. After the wavefront error of human eye had been corrected by the deformable membrane mirror under the control of a computer, the imaging illumination light was triggered by a electronic shutter to illuminate the retina, the images were captured by a CCD camera. It has been showed in model eye's test that the system could measure and correct the eye's wavefront aberration efficiently. The fundus image achieved the diffraction limit after aberration correction. It was showed in clinic that except a few patients with turbid eye, most patients could finish the process of measuring and correcting wavefront aberration and then taking fundus image. The examination process could be finished safely, quickly and reliably.
Keywords:MEMS   fundus   microscopic imaging
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