首页 | 本学科首页   官方微博 | 高级检索  
     

第二原发胰腺癌临床特征分析
引用本文:邹晓平,余志良,周国中,李兆申,胡先贵,王强,蔡全才,贺佳. 第二原发胰腺癌临床特征分析[J]. 第二军医大学学报, 2003, 24(9): 971-975
作者姓名:邹晓平  余志良  周国中  李兆申  胡先贵  王强  蔡全才  贺佳
作者单位:1. 第二军医大学长海医院消化内科,上海,200433
2. 长海医院普通外科
3. 长征医院普通外科
4. 卫生勤务学系流行病学教研室
5. 卫生勤务学系统计学教研室
基金项目:PLAClinicalHigh TechKeyProgram(Houweizi2 0 0 2 2 0 )
摘    要:目的:探讨第二原发胰腺癌的临床特征.方法:以96例普通原发胰腺癌作为对照,回顾性分析了病理确诊的32例第二原发胰腺癌的临床特征.结果:32例第二原发胰腺癌15例(46.9%)发生于乳腺癌、胃癌之后.性别、年龄、部位、临床症状、常规实验室检查及肿瘤标志物检测与普通进展期胰腺癌具有可比性,仅年龄略为提前,消化不良稍多,腹痛、黄疸比例稍降.B型超声、CT、MRI、逆行胰胆管造影诊断敏感率较普通胰腺癌高.处于Ⅰ期者仅2例(6.3%).总体半年存活率为50.0%,较普通胰腺癌略低.病理显示84.4%为腺癌,分化差.结论:第二原发胰腺癌症状更不典型,诊断更为滞后,预后更差,故应加强联系与第一次癌肿的早期检测手段(如肿瘤标志物)研究.

关 键 词:第二原发胰腺癌、诊断、预后

Clinical features of second primary pancreatic cancer
Abstract. Clinical features of second primary pancreatic cancer[J]. Former Academic Journal of Second Military Medical University, 2003, 24(9): 971-975
Authors:Abstract
Abstract:Objective:To study the clinical features of second primary pancreatic cancer(PC).Methods:The clinical features of 32 cases pathologically diagnosed second primary PC were retrospectively analyzed in detail,and 96 cases of common primary PC were taken as control.Results:Among 32 second primary PC patients, 15(46.9%) occurred after breast cancer or gastric cancer.Of sex,age,location of neoplasms,clinical symptoms,routine laboratory tests and assay of tumor markers,there were no significant differences between second primary PC and primary PC; only the age was a little younger than that of common PC; the percentage of dyspepsia was slightly higher;the percentages of abdominal pain and jaundice were slightly lower.The sensitivities of abdominal ultrasonography,spiral computed tomography(SCT),magnetic resonance imaging(MRI) and endoscopic retrograde cholangiopancreatography(ERCP) in diagnosis of second primary PC were higher than that of common PC.Only 2 patients(6.3%) were in stage Ⅰ.The total half-year survival rate was 52.0% for second primary PC,which was lower than that of common PC.Conclusion:The symptoms of second primary PC are more atypical than that of common PC,so the diagnosis is more difficult,and the prognosis is even worse.We should pay more attention to the studies of early detection measures(such as tumor markers) associated with the first primary cancers.
Keywords:second primary  pancreatic neoplasms  diagnosis  prognosis
本文献已被 CNKI 维普 万方数据 等数据库收录!
点击此处可从《第二军医大学学报》浏览原始摘要信息
点击此处可从《第二军医大学学报》下载全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号