| 尼群地平速释片与普通片的溶出度比较 |
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| 引用本文： | 陈晓燕,黄坚伟,汪茂先,尤孝庆. 尼群地平速释片与普通片的溶出度比较[J]. 中国医药工业杂志, 2001, 32(5): 213-214 |
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| 作者姓名： | 陈晓燕 黄坚伟 汪茂先 尤孝庆 |
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| 作者单位： | 广州白云山制药总厂药物研究所, |
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| 摘 要： | 将尼群地平与聚乙烯吡咯烷酮固体分散体制成速释片，其溶出度与自制及市售国产普通片相比，有明显提高，在含10％乙醇的人工胃液中20min的累积溶出度为70．8％，而自制及市售国产普通片分别为22．7％和21．3％。
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| 关 键 词： | 尼群地平 固体分散体 速释片 溶出度 钙拮抗剂 |
| 文章编号： | 1001-8255(2001)05-0213-02 |
| 修稿时间： | 2000-01-19 |
Comparison of Dissolution of Nitrendipine Fast-release and Usual Tablets |
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| CHEN Xiao-Yan,HUANG Jian-wei,WANG Mao-Xian,YOU Xiao-qing. Comparison of Dissolution of Nitrendipine Fast-release and Usual Tablets[J]. , 2001, 32(5): 213-214 |
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| Authors: | CHEN Xiao-Yan HUANG Jian-wei WANG Mao-Xian YOU Xiao-qing |
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| Abstract: | Nitrendipine fast release tablets were prepared by solid dispersion technique using polyvinylpyrrolidone. The dissolution test showed that the fast release tablets released much faster than the usual ones. |
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| Keywords: | nitrendipine solid dispersion fast-release tablets dissolution |
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