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神经节苷脂GM1治疗新生儿缺氧缺血性脑病30例疗效观察
引用本文:伍根峰,谢俊英,马友凤.神经节苷脂GM1治疗新生儿缺氧缺血性脑病30例疗效观察[J].中国实用神经疾病杂志,2011,14(9):27-28.
作者姓名:伍根峰  谢俊英  马友凤
作者单位:河南开封市儿童医院新生儿科,开封,475000
摘    要:目的 探讨神经节苷脂GM1治疗新生儿HIE的疗效.方法 将60例HIE新生儿按照有无接受神经节苷脂GM1治疗分为治疗组和对照组各30例,比较2组治疗前后的神经行为评分(NBNA).结果 治疗组生后20 d时NBNA评分较对照组明显升高(25.700±2.706 vs 21.833±2.214),差异具有统计学意义.结论...

关 键 词:神经节苷脂GM1  新生儿缺氧缺血性脑病  新生儿行为神经测定(NBNA评分)

Observation on the curative effect of ganglioside GM1 on neonatal hypoxic ischemic encephalopathy
Wu Genfeng,Xie Junying,Ma Youfeng.Observation on the curative effect of ganglioside GM1 on neonatal hypoxic ischemic encephalopathy[J].Chinese Journal of Practical Neruous Diseases,2011,14(9):27-28.
Authors:Wu Genfeng  Xie Junying  Ma Youfeng
Institution:.Department of Neonatology,Kaifeng Children’s Hospital,Kaifeng 472000,China
Abstract:Objective To evaluate the curative effect of ganglioside GM1 on neonatal hypoxic ischemic encephalopathy(HIE).Methods Sixty neonates HIE were divided into two groups:GM1 treated group(n=30) and control group(n=30),and neonatal behavioral neurological assessment(NBNA) scores were evaluated before and after treatment.Results When 20 days after birth of the neonatal in treatment group,NBNA scores were significantly higher than the control group(25.700±2.706 vs 21.833±2.214),there was a statistically significant difference.Conclusion Ganglioside GM1 can effectively improve the HIE newborns NBNA and improve the prognosis.
Keywords:Ganglioside GM1  Hypoxic ischemic encephalopathy  Neonatal behavioral neurological assessment
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