氯米帕明与认知疗法治疗青少年强迫症临床探讨

目的研究氯米帕明合并认知疗法对青少年强迫症的疗效。方法对30例服用氯米帕明效果不佳的青少年强迫症患者,采用氯米帕明合并认知疗法治疗,应用Hamilton焦虑量表(HAMA)、Yale-Brown强迫量表(Y-BOCS)和临床疗效量表(CGI-SI)于治疗前及治疗第2、4、8周末进行测评。以Y-BOCS减分率来评定疗效。结果疗程结束后,有效率80%,各量表评分均明显下降。结论氯米帕明合并认知疗法对青少年强迫症有较好疗效。

Study on cognitive therapy combined with clomipramine in treating adolescent obsessive disorder

Objective To observe the curative effects of clomipramine combined with cognitive therapy on adolescent patients with obsessive-compulsive disorder(OCD).Methods Thirty adolescent patients who were not satisfactory with clomipramine only,were given clomipramine combined with cognitive therapy.The effects were assessed with the Yale-Brown obsessive compulsive symptom scale(Y-BOCS),the Hamilton anxiety scale(HAMA) and clinical globol impression(CGI-SI) before and after the treatment.Results After 8 weeks,the results based on the reduction rate of Y-BOCS showed that the response rate was 80%,all rating scale marks were descended significantly.Conclusion Clomipramine combined with cognitive therapy is effective in treating refractory adolescent OCD.