Plasmapheresis treatment of antibody‐mediated rejection in an A2 donor to O pediatric liver transplant recipient |
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| Authors: | T. Martin J. Schwartz A. Demetris J. Comstock A. Lowichik L. Book |
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| Affiliation: | 1. Division of GI/Hepatology and Liver Transplantation, Department of Pediatrics, University of Utah Hospital, Salt Lake City, UT;2. Section of Transplantation, Department of Surgery, University of Utah Hospital, Salt Lake City, UT;3. University of Pittsburgh Medical Center, Pittsburgh, PA;4. Department of Pathology, University of Utah Hospital, Salt Lake City, UT, USA |
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| Abstract: | Martin T, Schwartz J, Demetris A, Comstock J, Lowichik A, Book L. Plasmapheresis treatment of antibody‐mediated rejection in an A2 donor to O pediatric liver transplant recipient.
Pediatr Transplantation 2011: 15:E15–E18. © 2009 John Wiley & Sons A/S. Abstract: It is safe to transplant kidneys from blood group A2 donors into O recipients if the latter have low titers of anti‐A antibodies. However, in liver transplantation, O and B recipients of A2 donor livers are not routinely screened for anti‐blood group antibodies because of the immuno‐absorptive capacity of the liver and the low incidence of antibody‐mediated rejection. Herein, we report a rare case of combined cell and antibody‐mediated rejection in a pediatric blood group O recipient of an A2 donor liver, and rescue of the allograft using PP and IVIG. |
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| Keywords: | antibody‐mediated rejection pediatric liver transplantation plasmapheresis humoral rejection |
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