冠状动脉旁路移植术后静脉桥狭窄的研究进展

冠状动脉旁路移植术是冠状动脉粥样硬化性心脏病的常规治疗方法之一.动脉血管作为移植血管材料有其自身优势,但对大多数患者而言,自体大隐静脉仍然是最常用的移植血管材料.新内膜形成和动脉粥样硬化导致的静脉桥再狭窄已成为一个亟待解决的问题.主要的防治方法包括药物、血管外支架、扩张液和基因治疗等,其中基因治疗为再狭窄的防治带来了新的前景.

Progression of research on re-stenosis of saphenous vein grafts after coronary artery bypass grafting

Coronary artery bypass grafting is one of the conventional treatment of coronary heart disease.Though the artery grafts have its own superiority,autologous saphenous vein is still commonly used.The restenosis of vein grafts which result from neointima and atherosclerosis has became an urgent problem to be resolved.Drug,external stent,expanding solution and gene therapy are the main methods of prevention of grafting occlusion,of which the gene therapy sheds new light on the resolution of vein grafts restenosis.