| 尪旭痹颗粒质量标准的研究 |
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| 引用本文： | 周春玲,林鹏,崔小路.尪旭痹颗粒质量标准的研究[J].中国药师,2010,13(6):780-782. |
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| 作者姓名： | 周春玲 林鹏 崔小路 |
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| 作者单位： | 1. 辽宁省食品药品检验所,沈阳,110023
2. 辽宁好护士药业有限公司 |
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| 基金项目： | 《中国药典》2010年版一部标准研究课题 |
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| 摘 要： | 目的：建立尪痹颗粒的质量控制方法.方法：用薄层色谱法对白芍、知母进行定性鉴别 高效液相色谱法对淫羊藿苷进行含量测定.结果：薄层色谱中均能明显地检出白芍、知母,淫羊藿苷在0.027 0～0.675 5μg·ml-1范围内,浓度与峰面积呈良好的线性关系（r=0.999 9）,平均回收率为100.0%,RSD=0.5%（n=9）.结论：本法简便准确,专属性强,可以作为该制剂的质量控制方法.
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| 关 键 词： | 尪痹颗粒 芍药苷 菝契皂苷元 淫羊藿苷 TLC HPLC |
Study on Quality Standard for Wangbi Granules |
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| Zhou Chunling,Lie Peng,Cui Xiaolu.Study on Quality Standard for Wangbi Granules[J].China Pharmacist,2010,13(6):780-782. |
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| Authors: | Zhou Chunling Lie Peng Cui Xiaolu |
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| Institution: | 1. Liaoning Institute for Food and Drug Control, Shenyang 110023, China;2. Liaoning Haohushi Medical ＆ Pharmaceutical Co. Ltd ) |
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| Abstract: | Objective： To establish a method for the quality control of wangbi granules. Method： Radix paeoriae alba and Anemarrhenae Rhizoma could be identified by TLC ; The HPLC for determination Icariin was conducted on an Agilent Cls （250 mm × 4. 6 mm, 5 μm） column with methanol-water-glacial acetic acid （55： 44：1 ） as mobile phase at the flow rate of 1.0 ml. min - 1, detection wave- length was set at 270 nm. Result： The calibration curve of icariin was linear within the range of 0. 027 0-0. 675 5 μg.ml-1 （r =0. 999 9）. The average recovery was 100. 0% with RSD of 0. 5% （n =9）. Conclusion： The method is simple,accurate,and suitable for the determination of paeoniflorin, sarsasapogenin and icariin in wangbi granules. |
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| Keywords: | TLC HPLC |
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