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Stabilization of warfarin‐binding pocket of VKORC1 and VKORL1 by a peripheral region determines their different sensitivity to warfarin inhibition |
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| Authors: | G. Shen S. Li W. Cui S. Liu Q. Liu Y. Yang M. Gross W. Li |
| Affiliation: | 1. Institute of Hemostasis and Thrombosis, College of Medicine, Henan University of Science and Technology, Luoyang, Henan, China;2. Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA;3. Department of Chemistry, Washington University in St. Louis, St. Louis, MO, USA;4. Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China |
| Abstract: | |
| Keywords: | blood coagulation drug resistance vitamin K vitamin K epoxide reductases warfarin |