| 芦笋对二甲基肼诱发小鼠结肠隐窝上皮细胞微核及凋谢的拮抗作用 |
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| 引用本文： | 孙含笑,祝庆蕃,付淑莉,王永军,窦桂荣,安玉会.芦笋对二甲基肼诱发小鼠结肠隐窝上皮细胞微核及凋谢的拮抗作用[J].郑州大学学报(医学版),1991(1). |
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| 作者姓名： | 孙含笑 祝庆蕃 付淑莉 王永军 窦桂荣 安玉会 |
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| 作者单位： | 河南医科大学病理学教研室
(孙含笑,祝庆蕃,付淑莉,王永军,窦桂荣),河南医科大学病理学教研室(安玉会) |
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| 摘 要： | 观察芦笋口服液对二甲基肼处理小鼠的结肠隐窝上皮细胞微核和凋谢的影响。结果显示芦笋口服液可降低结肠隐窝上皮细胞的微核和凋谢数,并有剂量效应关系。说明芦笋有明显的拮抗作用。此方法可作为抗结肠致癌物的短期试验。
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| 关 键 词： | 微核 凋谢 芦笋 抗结肠致癌物 |
Antagonistic effect of asparagus on DMH-induced micronuclei and apoptosis in the colon crypt cells of mouse |
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| Sun Hanxiao,Zhu Qingfan,Fu Shuli,Wang Yongjun,Dou Guirong,An Yuhui.Antagonistic effect of asparagus on DMH-induced micronuclei and apoptosis in the colon crypt cells of mouse[J].Journal of Zhengzhou University: Med Sci,1991(1). |
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| Authors: | Sun Hanxiao Zhu Qingfan Fu Shuli Wang Yongjun Dou Guirong An Yuhui |
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| Institution: | Sun Hanxiao;Zhu Qingfan;Fu Shuli;Wang Yongjun;Dou Guirong;An Yuhui Department of pathology |
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| Abstract: | The effect of asparagus on micronuclei and apoptosis in the colon crypt cellsof mice induced by DMH (1, 2-dimethylhydrazine) was observed by means ofstomach intubation of the "Oral Liquid of Asparagus". The result showed that theoral Liquid may reduce the incidence of the micronuclei and apoptosis of thecoloncrypt cells induced by DMH. This indicat that asparagus has marked anatonis-tic effects. This method may contribute to the short-term assay for anticoloncarcinogens |
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| Keywords: | asparagus micronuclei apoptosis anticolon-carcinogens |
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