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Mitochondria‐targeted antioxidant mitoquinone deactivates human and rat hepatic stellate cells and reduces portal hypertension in cirrhotic rats |
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| Authors: | Marina Vilaseca Héctor García‐Calderó Erica Lafoz Maria Ruart Cristina Isabel López‐Sanjurjo Michael P. Murphy Ramon Deulofeu Jaume Bosch Virginia Hernández‐Gea Jordi Gracia‐Sancho Juan Carlos García‐Pagán |
| Affiliation: | 1. Barcelona Hepatic Hemodynamic Laboratory, Liver Unit, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic de Barcelona, University of Barcelona Medical School, Barcelona, Spain;2. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain;3. MRC Mitochondrial Biology Unit, Cambridge, UK;4. Department of Biochemistry and Chromatography, Hospital Clinic de Barcelona, Barcelona, Spain |
| Abstract: | |
| Keywords: | cirrhosis hepatic haemodynamic hepatic stellate cells liver oxidative stress |