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爵床中一个新的木脂体苷——爵床苷E
引用本文:吴威巍,缪刘萍,王鑫杰,吴彤. 爵床中一个新的木脂体苷——爵床苷E[J]. 中国医药工业杂志, 2012, 43(8): 669-672
作者姓名:吴威巍  缪刘萍  王鑫杰  吴彤
作者单位:1. 上海杨浦科技创业中心有限公司,上海,200433
2. 中国医药工业研究总院上海医药工业研究院,创新药物与制药工艺国家重点实验室,上海200040
摘    要:用硅胶柱色谱和Sephadex LH-20柱色谱对安徽产爵床(Justicia procumbens L.)全草乙醇提取物的乙酸乙酯和正丁醇部位进行分离纯化,得到6个单体化合物,通过IR、NMR等波谱技术以及一些化学方法推测化合物结构,分别为爵床脂素A(1)、新爵床脂素B(2)、爵床脂素B(3)、爵床苷B(4)、尿嘧啶(5)和爵床苷E(6),其中6为新的木脂体苷类化合物。

关 键 词:爵床  爵床脂素  尿嘧啶  爵床苷  结构解析

A New Lignan Glycoside Procumbenoside E from Justicia Procumbens L.
WU Weiwei , MIAO Liuping , WANG Xinjie , WU Tong. A New Lignan Glycoside Procumbenoside E from Justicia Procumbens L.[J]. , 2012, 43(8): 669-672
Authors:WU Weiwei    MIAO Liuping    WANG Xinjie    WU Tong
Affiliation:1.Shanghai Yangpu Innovation Center Ltd.,Shanghai 200433;2.State Key Lab.of New Drug & Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry,China State Institute of Pharmaceutical Industry,Shangai 200040)
Abstract:The chemical constituents from the overground portion of Justicia procumbens L.were studied.Silica gel and Sephadex LH-20 column chromatographic techniques were used for the isolation and purification of the chemical constituents of the ethyl acetate and n-butanol portion of the plant.Six compounds,identified as justicidin A(1),neojusticin B(2),justicidin B(3),procumbenoside B(4),uracil(5) and procumbenoside E(6),were isolated and their structures were elucidated by the means of IR,MS and NMR spectroscopy and some chemical methods.Among them,compound 6 was a new compound isolated from Justicia procumbens L.
Keywords:Justicia procumbens L.  justicidin  uracil  procumbenoside  identification
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