| 早产儿脑损伤的患病率和危险因素 |
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| 引用本文： | 田鸾英.早产儿脑损伤的患病率和危险因素[J].实用儿科临床杂志,2011,26(2):128-130. |
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| 作者姓名： | 田鸾英 |
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| 作者单位： | 深圳市南山区妇幼保健院,新生儿科,广东,深圳,518052 |
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| 摘 要： | 目的 探讨早产儿脑损伤的患病率和危险因素,为预防或降低早产儿脑损伤提供依据.方法 对2005年1月-2006年12月美国圣路易斯华盛顿大学儿童医院NICU收治的胎龄小于37周的早产儿的临床资料进行回顾性分析,按胎龄分组,计算脑损伤的患病率,采用多因素Logistic回归模型确立危险因素.结果 本组早产儿总的脑室内出血(IVH)和脑室周围白质软化(PVL)的患病率分别为17.7%和4.9%,而存活病例的患病率分别为14.4%和4.5%.按胎龄分组,IVH和PVL的患病率分别为:23~<25周龄组48.1% 和14.8%、25~<28周龄组35.2%和11.2%、28~<33周龄组13.8%和3.1%、33~<37周龄组2.8%和1.7%.坏死性小肠结肠炎、PDA、机械通气(MV)是IVH的独立危险因素,而胎龄、5 min Apgar评分为保护因素(负相关);IVH、MV、母亲产前或产时感染是PVL的危险因素,而出生体质量和女性为保护因素.同时IVH是导致早产儿死亡的危险因素.结论 胎龄越小,脑损伤的患病率越高;围生期感染、窒息缺氧以及影响脑血流的因素如PDA和MV等与早产儿脑损伤的发生密切相关.
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| 关 键 词： | 脑损伤 高危因素 患病率 婴儿 早产 |
Incidence and Risk Factors of Brain Injury in Preterm Infants |
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| TIAN Luan-ying.Incidence and Risk Factors of Brain Injury in Preterm Infants[J].Journal of Applied Clinical Pediatrics,2011,26(2):128-130. |
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| Authors: | TIAN Luan-ying |
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| Institution: | TIAN Luan-ying(Department of Neonatology,Nanshan Maternal and Child Care Service Center,Shenzhen 518052,Guangdong Province,China) |
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| Abstract: | Objective To explore the incidence and risk factors of brain injury in preterm infants and provide basic data for prevention of brain injury and improvement of outcome in preterm infants.Methods Data were collected retrospectively among neonates with gestational age of< 37 weeks,who were admitted to NICU in St.Louis Children's Hospital in Washington University School of Medicine from Jan.2005 to Dec.2006.Intraventricular haemorrhage(IVH)and periventricular leukomalacia(PVL)rates were calculated by gestation... |
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| Keywords: | brain injury risk factor incidence preterm infant |
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