| 非血缘造血干细胞移植现状与问题 |
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| 引用本文： | 傅华睿,黄河.非血缘造血干细胞移植现状与问题[J].中国实用内科杂志,2011,31(2):146. |
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| 作者姓名： | 傅华睿 黄河 |
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| 作者单位： | 浙江大学医学院附属第一医院骨髓移植中心; |
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| 摘 要： | 异基因造血干细胞移植(Allo HSCT)是某些血液系统恶性疾病惟一有望治愈的手段，也是某些血液系统非恶性疾病的重要治疗手段。HLA相合同胞供者是Allo HSCT首选的供者来源，但是只有部分患者可以找到相合的同胞供者。因此，寻找合适的非血缘供者就变得十分重要。近年来，随着移植技术方案的成熟和支持治疗的进步，移植现状已获得明显的改善，非血缘供者造血干细胞移植疗效已达到了与同胞供者移植接近的水平。
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| 关 键 词： | 造血干细胞移植 同胞供者 非血缘供者 人类白细胞抗原 |
Current situation and problems for allogeneic hematopoietic stem cell transplantation |
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| FU Hua-rui,HUANG He.Current situation and problems for allogeneic hematopoietic stem cell transplantation[J].Chinese Journal of Practical Internal Medicine,2011,31(2):146. |
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| Authors: | FU Hua-rui HUANG He |
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| Institution: | FU Hua-rui,HUANG He.Center of Bone Marrow Transplantation,First Hospital of Zhejiang University,Hangzhou 31003,China |
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| Abstract: | Allogeneic hematopoietic stem cell transplantation(Allo-HSCT) has been the only promising approach for a curative treatment of certain hematological malignancies and also an important intervention for some of non-malignant diseases.Since matched sibling donors are the first candidates among all donor sources,only a small percentage of patients may have matched sibling donors.For those who do not,search of matched unrelated donor remains extremely important.In recent years,along with mature of transplantatio... |
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| Keywords: | hematopoietic stem cell transplantation sibling donor unrelated donor HLA |
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