米非司酮配伍米索前列醇对早孕妇女流产效果的影响分析

目的:探讨米非司酮配伍米索前列醇对早孕妇女流产效果的影响。方法:选取早孕妇女100例,按≤49 d、50～70 d编号后分为两组:Ⅰ组、Ⅱ组各50例,两组均采用米非司酮每天晨口服50 mg。晚口服25 mg,间隔12 h,服药前后2 h空腹。共服2 d。第3天晨空腹服米索前列醇600μg。留院观察。观察两组的完全流产率及两种药物流产方案的阴道出血发生率和阴道流血时间。结果:两组的完全流产率比较,差异无统计学意义(P>0.05);Ⅰ组阴道流血发生率明显低于Ⅱ组(P<0.05),但两组阴道出时间比较,差异无统计学意义(P>0.05)。结论:妊娠期≤49 d口服米非司酮配伍米索前列醇对早孕妇女流产效果满意,值得借鉴。

Mifepristone and misoprostol on women in early pregnancy abortion effect analysis

Objective To investigate the mifepristone and misoprostol on women in early pregnancy abortion effect.Methods Choose 100 cases of pregnant women,according to 49 d,50～70 d number is divided into 2 groups:Ⅰgroup,Ⅱgroup with 50 cases in each group,two groups were using mifepristone morning oral 50 mg.Late oral 25 mg,at intervals of 12 hours,2 hours of fasting before and after medication.Take 2 days in all.Third days morning fasting dose misoprostol 600 μg.In hospital observation.The complete abortion rate was observed in the two groups and the two regimens for medical abortion vaginal bleeding incidence and vaginal bleeding time.Results the complete abortion rate of two groups had no significant differences(P>0.05);group Ⅰ vaginal bleeding incidence rate was significantly lower than that in Ⅱ group(P<0.05),but the two groups of vaginal time had no significant differences(P>0.05).Conclusion Pregnancy is less than or equal to 49 d oral mifepristone and misoprostol on women in early pregnancy abortion effect is satisfactory,worth learning.