2型糖尿病患者不同部位骨密度测定对结果的影响

目的探讨2型糖尿病患者不同部位的骨密度测定对结果的影响.方法分别采用定量CT(quantitative CT,QCT)和SXA(单能X线)测量了2型糖尿病患者腰椎松质骨的骨密度(bone mineral density,BMD)与脚跟骨的骨密度.结果各年龄组男女患者的骨密度与正常对照组相比均无显著性差异;糖尿病合并肾病组QCT测得的椎体骨密度明显低于无肾病组,而SXA测得的跟骨骨密度在女性低于无肾病组,男性则无差异.结论2型糖尿病肾病会导致骨量减少,但测量仪器、测量部位以及分组方法的不同会影响所得的结果.

Influence of bone mineral density measurement at different sites on results in type Ⅱ diabetes

Objective: To study the influence of bone mineral density measurement at different sites on the results in type Ⅱ diabetes. Methods: The bone mineral density of lumbar and calcaneus was measured by quantitative CT(QCT) and SXA respectively. Results: There was no significant difference between the bone mineral density of patients and that of normal control group. The bone mineral density of lumbar measured by QCT in diabetic nephropathy group was obviously lower than that in patients without diabetic nephropathy. In female patients, the bone mineral density of calcaneus in diabetic nephropathy group measured by SXA was lower than that in patients without diabetic nephropathy, but in male patinets there was no difference. Conclusions: Diabetic nephropathy causes bone density decline and the result changes with different measurement apparatus, sites and different grouping methods.