盐酸氨溴索联合碳酸氢钠用于吸入性损伤气管切开病人气道湿化的临床观察

目的]观察盐酸氨溴索联合碳酸氢钠用于吸入性损伤气管切开病人气道湿化的效果。方法]将2013年6月—2016年5月烧伤科70例因吸入性损伤行气管切开的成人病人按随机数字表法分为对照组和观察组各35例,对照组在气管切开的常规护理基础上采用传统的糜蛋白酶、硫酸庆大霉素、地塞米松磷酸钠及生理盐水作为气道湿化液,使用持续微量注射泵滴入气道湿化法,观察组在气管切开的常规护理基础上采用盐酸氨溴索+1.25%碳酸氢钠作为湿化液,使用持续微量注射泵滴入气道湿化法。比较两组病人并发症发生情况、气道湿化效果。结果]观察组病人痰痂形成、呼吸道感染、刺激性咳嗽、气道黏膜损伤和出血等并发症发生率低于对照组(P0.05),湿化效果优于对照组(P0.05)。结论]盐酸氨溴索联合碳酸氢钠用于吸入性损伤气管切开术后病人气道湿化的效果明显,并发症发生率低,效果优于传统的糜蛋白酶、硫酸庆大霉素、地塞米松磷酸钠及生理盐水作为气道湿化液。

Clinical observation of ambroxol combined with sodium bicarbonate for airway humidification in tracheotomy pa-tients with inhalation inj ury

Objective:To observe the effect of ambroxol combined with sodium bicarbonate on airway humidifica-tion in patients with traumatic tracheotomy.Methods:Total of 70 patients with tracheal incision who underwent tracheotomy were randomly divided into control group(35 cases)and observation group(35 cases)in the burn department from June 2013 to May 2016.The control group were treated with conventional care on the basis of the traditional chymotrypsin gentamicin sulfate combined with dexamethasone sodium phosphate and saline as humidified airway liquid,carried out the continuous micro infusion pump airway wetting method.The observa-tion group use ambroxol hydrochloride+1.25% sodium bicarbonate as humidified airway liquid on the basic nursing routine,carried out the continuous micro infusion pump airway wetting method.The complication and airway humidification effect were compared between the two groups.Results:The incidences of sputum forma-tion,respiratory tract infection,irritable cough,airway mucosal inj ury and hemorrhage in the observation group were lower than those in the control group(P<0.05),and the wetting effect was better than the control group (P<0.05).Conclusion:Ambroxol combined with sodium bicarbonate for airway humidification after inhalation inj ury tracheotomy was effective,which has low incidence of complications,and the effect is better than the tra-ditional chymotrypsin gentamicin sulfate,Dexamethasone sodium phosphate and saline as airway humidification solution.