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抗生素骨水泥及念珠预防和治疗骨科感染
引用本文:陈曦,范卫民,王黎明,沈海琦.抗生素骨水泥及念珠预防和治疗骨科感染[J].现代医学,2002,30(5):348-350.
作者姓名:陈曦  范卫民  王黎明  沈海琦
作者单位:1. 南京医科大学附属南京市第一医院骨科,江苏南京,210006
2. 南京医科大学第一附属医院骨科,江苏南京,210029
摘    要:局部使用抗生素防治骨科感染由来已久。随着关节置换术的广泛开展,应用抗生素骨水泥预防和治疗关节置换术术后感染重新被重视,抗生素骨水泥念珠也被用于慢性骨髓炎的预防和治疗及修复开放性骨折时的感染预防。目前,被关注的问题主要有两个:(1)各种新的抗生素加入骨水泥后的有效性和安全性;(2)抗生素对骨水泥物理性质的影响。

关 键 词:抗生素骨水泥  洗提  压缩强度  弯曲模量  弯曲强度  预防  治疗  骨科感染
文章编号:1671-7563(2002)05-0348-03
修稿时间:2002年3月22日

Antibiotic-impregnated cement and beads for orthopaedic infections
CHEN Xi ,FAN Wei min ,WANG Li ming ,SHEN Hai qi.Antibiotic-impregnated cement and beads for orthopaedic infections[J].Modern Medical JOurnal,2002,30(5):348-350.
Authors:CHEN Xi  FAN Wei min  WANG Li ming  SHEN Hai qi
Institution:CHEN Xi 1,FAN Wei min 2,WANG Li ming 1,SHEN Hai qi 1
Abstract:It is a long history of local antibiotic use for the treatment of orthopaedic infections.The local use of antibiotics impregnated cement to prevent and treat skeletal infections is revived with the widespread use of arthroplasties.The beads are used to prevent infections after open fractures repair and treat chronic osteomyelitis.Now,two unresolved questions are paid attention to:(1)The efficacy and the safty for various antibiotics which are impregnated into the cement.The elution characteristics are important data for the efficacy of antibiotics;(2)The effect of antibiotics on the mechanical properties of bone cement.
Keywords:antibiotic  impregnated cement  elution  compressive strength  bending modulus  bending strength
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