隔姜灸对结直肠癌行腹腔镜根治术后凝血功能的影响

目的 探讨隔姜灸对结直肠癌行腹腔镜根治术后凝血功能的影响。方法 采用随机数字表法,将96例结直肠癌行腹腔镜根治术患者分为2组,对照组、观察组各48例。2组患者术后均给予胃肠外科术后常规护理,观察组施以隔姜灸,比较2组术前第1天、术后第1天及术后第7天凝血功能指标的变化。结果 与对照组相比,观察组的凝血酶原时间、活化部分凝血活酶时间在组间效应、时间效应、交互作用的比较,差异具有统计学意义（P<0.05）;血浆抗凝血酶Ⅲ活性测定在组间效应、时间效应的比较,差异具有统计学意义（P<0.05）,在交互作用的比较,差异无统计学意义（P>0.05）;2组凝血酶时间、纤维蛋白原、D-二聚体在时间效应的比较,差异具有统计学意义（P<0.05）,在治疗效应、交互作用的比较,差异均无统计学意义（P>0.05）。结论 隔姜灸能够影响凝血功能指标,有效改善结直肠癌行腹腔镜根治术后患者的血液高凝状态。

Effect of Ginger-separated Moxibustion on Blood Coagulation after Laparoscopic Radical Resection of Colorectal Cancer

Objective To investigate the effect of ginger-separated moxibustion on coagulation function after laparoscopic radical resection of colorectal cancer. Methods Totally 96 patients with colorectal cancer undergoing laparoscopic radical resection were divided into control group (n=48) and experimental group (n=48). The patients in the two groups were given routine postoperative care and the experimental group was given ginger moxibustion additionally. The changes of coagulation function were compared between the two groups 1 day before, 1 day and 7 days after the operation. Results The comparison of prothrombin time (PT) and activated partial thromboplastin time (APTT) between the two groups showed significant difference in terms of group effect, time effect and interaction (P<0.05). The group effect and time effect of antithrombin III (AT3) were significantly different between the two groups (P<0.05), but no difference was found in terms of interaction between groups (P>0.05). The time effect of thrombin time (TT), fibrinogen (FIB) and D-dimer were significantly different between the two groups (P<0.05), but there was no significant difference in group effect and interaction(P>0.05). Conclusion Ginger-separated moxibustion affects blood coagulation function and effectively improve the hypercoagulability of patients after laparoscopic radical resection of colorectal cancer.