| 体外反搏对休克犬血中SOD和MDA的影响 |
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| 引用本文： | 吴坤莹 唐妙云. 体外反搏对休克犬血中SOD和MDA的影响[J]. 中华创伤杂志, 1994, 10(1): 7-9 |
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| 作者姓名： | 吴坤莹 唐妙云 |
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| 作者单位： | Wu Kunying，Zhao Ke-sen，Jiang Yong，et al. Dept. of Pathophysiology，1st Military Medical University，Guangzhou 510515 |
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| 摘 要： | 作者复制犬失血性休克模型。用改良的硫代巴比妥酸法测定血浆丙二醛（ＭＤＡ）含量，用光化学扩增法测定全血超氧歧化酶（ＳＯＤ）活性。观察ＷＦＢ－Ⅴ型电脑控制的增强型体外反搏机治疗失血性休克后对上述指标的影响。结果表明，犬失血性休克后血浆ＭＤＡ明显升高，全血ＳＯＤ活性显著下降。体外反搏治疗可使升高的ＭＤＡ含量降至正常水平，ＳＯＤ活性明显恢复，从而证明体外反搏治疗失血性休克时，并没有因微循环灌流的改善而带来
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| 关 键 词： | 休克 缺血 超氧物歧化酶 体外反搏 |
Effect of External Counterpulsation on the Activity of Blood SOD and Level of Plasma MDA During Hemorrhagic Shock in Dogs |
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| Wu Kunying,Zhao Ke-sen,Jiang Yong,et al.. Effect of External Counterpulsation on the Activity of Blood SOD and Level of Plasma MDA During Hemorrhagic Shock in Dogs[J]. Chinese Journal of Traumatology, 1994, 10(1): 7-9 |
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| Authors: | Wu Kunying Zhao Ke-sen Jiang Yong et al. |
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| Affiliation: | Wu Kunying,Zhao Ke-sen,Jiang Yong,et al. Dept. of Pathophysiology,1st Military Medical University,Guangzhou 510515 |
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| Abstract: | A model of hemorrhagic shock was reproduced in dogs. The level of plasma MDA and the activity of blood SOD were measured. The effect of external counterpulsation (EC) on the activity of blood SOD and the level of plasma MDA in hemorrhagic shock were observed. The results showed that the content of plasma MDA was increased and the activity of blood SOD was decreased apparently after hemorrhagic shock, and the increasing MDA level was returned to normal and the activity of decreased SOD was improved by administration of EC. The conclution is that EC treatment does not cause reperfusion injury, and may decrease the production of free radicals during hemorrhagic shock. |
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| Keywords: | Hemorrhagic shock SOD MDA External counterpulsation |
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