Characterization of divergent and atypical canine coronaviruses from Sweden |
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Authors: | S. Escutenaire M. Isaksson L. H. M. Renström B. Klingeborn C. Buonavoglia M. Berg S. Belák P. Thorén |
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Affiliation: | (1) Department of Virology, National Veterinary Institute (SVA), Uppsala, Sweden;(2) Department of Animal Health and Well-being, Faculty of Veterinary Medicine, Valenzano, Bari, Italy;(3) Section of Parasitology and Virology, Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences (SLU), Uppsala, Sweden |
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Abstract: | Summary Field canine coronaviruses (CCVs) identified during a series of outbreaks of gastroenteritis in Swedish dogs were subjected to genetic analysis involving the open reading frame 1b (ORF1b) and the membrane (M) and spike (S) protein genes. Four field viruses originating from the Stockholm region presented identical sequences and segregated separately from other CCVs characterized so far and from GOT/05, the variant recovered in Western Sweden. A recombinant origin of the fifth virus identified in the Stockholm region is suggested. In addition, the five viruses originating from the same geographical area displayed atypical 5′ S gene sequences. |
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