| 单纯放疗治疗早期声门型喉癌的系统评价 |
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| 引用本文： | 冯彦,王斌全,温树信. 单纯放疗治疗早期声门型喉癌的系统评价[J]. 中华医学图书情报杂志, 2010, 19(10): 53-56 |
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| 作者姓名： | 冯彦 王斌全 温树信 |
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| 作者单位： | 山西医科大学耳鼻咽喉头颈外科,山西太原,030001 |
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| 摘 要： | 目的:比较非常规分割放疗与常规分割放疗治疗早期声门型喉癌的疗效和副反应。方法:通过Cochrane中心临床对照试验注册数据库、MEDLINE、Embase,中国生物医学文献数据库(CBM)、中国期刊全文数据库以及中文科技期刊全文数据库检索列入非常规分割放疗与常规分割放疗治疗早期声门型喉癌病人的临床对照试验。结果:最终仅列入5个回顾性非随机临床对照试验,研究对象617例。Meta分析结果显示超分割放疗(HRT)与常规分割放射治疗(CF)相比可以提高早期声门型喉癌病人的5年局部控制率[RR=0.53,95%CI(0.29,0.94]。分段加速超分割放疗(SHART)和加速超分割放疗(HART)组的5年局部控制率与常规分割放疗组(CF)的差异无统计学意义。与CF相比,HRT、SHART和HART均未提高病人的5年总生存率[RR=1.13,95%CI(0.70,1.85)]。除Sakata等的研究认为非常规分割放疗与常规分割放疗比较明显增加了病人放疗后副反应的发生率外,其余研究均认为非常规分割放疗与常规分割放疗后副反应的发生率相似。结论:本系统评价由于列入研究病例数偏少,更缺乏准确的非常规分割放疗与常规分割放疗治疗早...
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| 关 键 词： | 早期声门型喉癌 系统评价 超分割放疗 加速分割放疗 |
| 收稿时间： | 2010-03-16 |
Simple radiotherapy for early glottic cancer: A systematic evaluation |
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| FENG Yan,WANG Bin-quan and WEN Shu-xin. Simple radiotherapy for early glottic cancer: A systematic evaluation[J]. Chinese Journal of Medical Library and Information Science, 2010, 19(10): 53-56 |
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| Authors: | FENG Yan WANG Bin-quan WEN Shu-xin |
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| Affiliation: | FENG Yan,WANG Bin-quan,WEN Shu-xin(Department of Otolaryngology,Head and Neck Surgery,Shanxi Medical University,Taiyuan 030001,Shanxi Province,China) |
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| Abstract: | Objective: To compare the efficiency and side effects of conventional fractionation radiotherapy and non-conventional fractionation radiotherapy for early glottic cancer.Methods: Clinical control trials of conventional fractionation radiotherapy and non-conventional fractionation radiotherapy for early glottic cancer were searched from Cochrane library,MEDLINR(OVID),EMbase,CBM,CNKI and VIP.Results: Five retrospective non-randomized trials involving 617 patients with early glottic cancer were included in thi... |
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| Keywords: | early glottic cancer hyperfractionated radiotherapy accelated fractionated radiotherapy systematic evaluation |
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