肉毒毒素对面肌痉挛治疗的研究进展

面肌痉挛是由一侧面神经支配的肌肉的不自主、不规则、阵挛性或紧张性收缩。随着病情的进 展，面肌痉挛症状加重可能会影响患者的日常生活，进而对患者的情绪产生负面影响，对面肌痉挛的治疗 是很有必要的。肉毒毒素的注射作为一种安全、有效的治疗方法，可以在3-6个月内改善患者面肌痉挛症 状。 本文通过对面肌痉挛的诊断及对生活的影响、肉毒毒素对面肌痉挛的治疗方法及原理进行总结，并 结合肉毒毒素疗效评估在面肌痉挛的进展进行论述，为肉毒毒素治疗面肌痉挛的疗效评估提供参考。

Research Progress of Botulinum Toxin in the Treatment of Hemifacial Spasm

Hemifacial spasm is an involuntary, irregular, clonic or tonic contraction of the muscles innervated by one side of the facial nerve. With the progress of the disease, the aggravation of hemifacial spasm symptoms may affect the daily life of patients, which in turn has a negative impact on the patient''s mood. It is necessary to treat hemifacial spasm. As a safe and effective treatment, botulinum toxin injection can improve the symptoms of hemifacial spasm within 3-6 months. This article summarizes the diagnosis of hemifacial spasm and its impact on life, the treatment methods and principles of botulinum toxin on hemifacial spasm, and discusses the progress of botulinum toxin efficacy evaluation in hemifacial spasm, so as to provide reference for the efficacy evaluation of botulinum toxin in the treatment of hemifacial spasm.