再生疗法和康复治疗的联合应用对神经疾病运动功能的康复效果：Scoping综述

目的 综述再生疗法和康复治疗联合应用于神经疾病运动功能的康复效果。方法 检索建库至2021年4月1日PubMed、Web of Science、中国知网、万方数据库中有关再生疗法和康复治疗相结合作用于神经疾病的相关研究,提取文献内容并进行Scoping综述。结果 共检索文献2567篇,最终纳入26篇,其中3篇为人类临床研究,23篇为动物基础研究。研究设计主要为随机或非随机对照试验、病例系列研究。研究主要涉及再生疗法和康复治疗的联合干预对脑卒中、脊髓损伤、脑性瘫痪等神经疾病运动功能的治疗效果。结论 本文从范畴上界定了再生康复在神经疾病的相关研究和应用,发现再生疗法和康复治疗的结合对于神经疾病运动功能的恢复具有一定的协同效应。未来需要更多的科研工作来支持其临床实践。

Effect of Combination of Regenerative Medicine and Rehabilitation on Motor Function of Neurological Diseases: A Scoping Review

Objective To perform a scoping review of the combination of regenerative therapy and rehabilitation in neurological diseases.Methods Literatures about the combination of regenerative therapy and rehabilitation in neurological diseases were retrieved in PubMed, Web of Science, CNKI and Wanfang data from establishment to April 1st, 2021.Results A total of 2567 literatures were retrieved, and 26 were finally enrolled, including three human clinical studies and 23 animal basic studies. The research design was mainly randomized or non-randomized controlled trials and case series. The researches mainly involved the therapeutic effect of combined regeneration therapy and rehabilitation on neurological diseases, such as stroke, spinal cord injury and cerebral palsy, etc.Conclusion The researches and applications of regenerative rehabilitation in neurological diseases were scoped, and it was found that the combination of regenerative therapy and rehabilitation has synergistic effects on the restoration of motor function of neurological diseases, and more scientific researches are needed to support its clinical practice in the future.