Rapid acoustic processing in the auditory brainstem is not related to cortical asymmetry for the syllable rate of speech |
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| Affiliation: | 1. Auditory Neuroscience Laboratory, Department of Communication Sciences, Northwestern University, 2240 Campus Drive, Evanston, IL 60208, USA;2. Departments of Neurobiology and Physiology and Otolaryngology, Northwestern University, 2240 Campus Drive, Evanston, IL 60208, USA;1. National Institute for Health Research, Nottingham Hearing Biomedical Research Unit, Nottingham, UK;2. Otology and Hearing Group, Division of Clinical Neuroscience, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK;3. Veterans Affairs Northern California Health Care System, Martinez, CA, USA;4. Rush University Medical Center, Chicago, IL, USA;1. Department of Pediatric Oncology, Erasmus MC – Sophia Children''s Hospital, Rotterdam, The Netherlands;2. Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands;3. Department of Phoniatrics and Pedaudiology, University of Münster, Münster, Germany;4. Department of Pediatric Oncology, Beatrix Children''s Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;5. Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands;6. Department of Pediatrics, VU University Medical Center, Amsterdam, The Netherlands;7. Department of Pediatric Stem Cell Transplantation, Willem-Alexander Children''s Hospital, Leiden University Medical Center, Leiden, The Netherlands;8. Department of Pediatric Oncology, Wilhelmina Children''s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands;9. Department of Pediatric Oncology, Academic Medical Center – Emma Children''s Hospital, Amsterdam, The Netherlands;1. Duke University Medical Center, Division of Otolaryngology-Head and Neck Surgery & Communication Sciences, Department of Surgery, 40 Duke Medicine Circle, DUMC 3805, Durham, NC 27710, USA;2. Duke University School of Medicine, 8 Duke University Medical Center Greenspace, Durham, NC 27703, USA;1. Department of Linguistics, Macquarie University, NSW, Australia;2. HEARing Co-operative Research Centre, Australia;3. National Acoustic Laboratories, NSW, Australia;1. Department of Neurology, Massachusetts General Hospital/Brigham and Women''s Hospital, Harvard Medical School, Boston, MA, USA;2. Department of Mathematics and Statistics, University of Vermont, Burlington, VT, USA;3. Department of Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, Philadelphia, PA, USA;4. Department of Psychiatry, Indiana University, Indianapolis, IA, USA;5. Division of Cardiology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA;6. Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA;7. Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA;8. Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, VT, USA;9. Section of Cardiology, Department of Medicine, Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA |
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| Abstract: | ObjectiveTemporal acuity in the auditory brainstem is correlated with left-dominant patterns of cortical asymmetry for processing rapid speech-sound stimuli. Here we investigate whether a similar relationship exists between brainstem processing of rapid speech components and cortical processing of syllable patterns in speech.MethodsWe measured brainstem and cortical evoked potentials in response to speech tokens in 23 children. We used established measures of auditory brainstem and cortical activity to examine functional relationships between these structures.ResultsWe found no relationship between brainstem responses to fast acoustic elements of speech and right-dominant cortical processing of syllable patterns.ConclusionsBrainstem processing of rapid elements in speech is not functionally related to rightward cortical asymmetry associated with the processing of syllable-rate features in speech. Viewed together with previous evidence linking brainstem timing with leftward cortical asymmetry for faster acoustic features, findings support the existence of distinct mechanisms for encoding rapid vs. slow elements of speech.SignificanceResults provide a fundamental advance in our knowledge of the segregation of sub-cortical input associated with cortical asymmetries for acoustic rate processing in the human auditory system. Implications of these findings for auditory perception, reading ability and development are discussed. |
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