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| 钠-葡萄糖共转运蛋白2抑制剂对心室重构的影响 | |
| 引用本文： | 李兆,程功. 钠-葡萄糖共转运蛋白2抑制剂对心室重构的影响[J]. 中国全科医学, 2021, 24(3): 267-271. DOI: 10.12114/j.issn.1007-9572.2020.00.638 |
| 作者姓名： | 李兆 程功 |
| 作者单位： | 1.710068陕西省西安市，西安医学院 2.710068陕西省西安市，陕西省人民医院心血管内二科 *通信作者：程功，主任医师；E-mail：xianchenggong@163.com |
| 摘 要： | 心室重构是多种心血管疾病进展过程中伴随的病理生理反应,心室重构越严重则心血管疾病患者预后越差,并最终导致心力衰竭及死亡,但目前临床可用于延缓或逆转心室重构的药物有限.钠-葡萄糖共转运蛋白2(SGLT-2)抑制剂是一种新型口服降糖药,已有多项研究表明其具有心血管保护作用.本文重点分析了SGLT-2抑制剂对急性心肌梗死、糖... |
| 关 键 词： | 心室重构 钠-葡萄糖转运体2 心肌梗死 糖尿病心肌病 高血压 心力衰竭 |
Effect of Sodium-glucose Co-transporter 2 Inhibitor on Ventricular Remodeling |
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| LI Zhao,CHENG Gong. Effect of Sodium-glucose Co-transporter 2 Inhibitor on Ventricular Remodeling[J]. Chinese General Practice, 2021, 24(3): 267-271. DOI: 10.12114/j.issn.1007-9572.2020.00.638 | |
| Authors: | LI Zhao CHENG Gong |
| Affiliation: | 1.Xi'an Medical University，Xi'an 710068，China 2.No.2 Department of Cardiology，Shaanxi Provincial People's Hospital，Xi'an 710068，China *Corresponding author：CHENG Gong，Chief physician；E-mail：xianchenggong@163.com |
| Abstract: | Ventricular remodeling is a pathophysiological process associated with the progression of cardiovascular diseases，the more severe of ventricular remodeling，the worse of prognosis of cardiovascular diseases，and it will eventually lead to heart failure and death.However，there are limited available drugs to delay or reverse ventricular remodeling clinically.As a new type of oral hypoglycemic drug，sodium-glucose co-transporter 2（SGLT-2）inhibitor has been indicated a protective effect on cardiovascular system by many studies.This paper selectively analyzed the effect of SGLT-2 inhibitor on ventricular remodeling in acute myocardial infarction，diabetic cardiomyopathy，hypertensive heart disease and heart failure，so as to provide a reference for more scientific and reasonable application of SGLT-2 inhibitor. |
| Keywords: | Ventricular remodeling Sodium-glucose transporter 2 Myocardial infarction Diabetic cardiomyopathies Hypertension Heart failure |
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