恶性肿瘤患者疾病不确定感与创伤后应激障碍相关性研究

目的：了解恶性肿瘤患者疾病不确定感及创伤后应激障碍水平，并探讨两者之间的关系。方法：便利抽样方法选取经病理确诊为恶性肿瘤的171例患者为研究对象，采用基线资料调查表、中文版疾病不确定感量表（MUIS-A）、PTSD筛查量表( PCL- C)进行问卷调查。 结果：恶性肿瘤患者MUIS- A总分为（90.75±11.64）分， PCL- C总分为(43.04±12.12)分，疾病不确定感总分与创伤后应激障碍总分、回避/麻木维度及高警觉维度呈正相关（P＜0.05），与重新体验维度相关性无统计学意义（P＞0.05）。结论：恶性肿瘤患者疾病不确定感及创伤后应激障碍均处于较高水平，并且两者呈正相关关系。临床工作中可以通过提供疾病相关信息，减少患者不确定感，减轻其的心理困扰，如创伤后应激障碍，澄清其对患病状态的模糊性，增加对未来的控制能力，最终提高其生存质量。

A correlational study on disease uncertainty and post-traumatic stress disorder in patients with malignant tumors

Objective:To investigate the level of uncertainty and post-traumatic stress disorder(PTSD) in patients with malignant tumors and to explore the relationship between them. Methods: 171 patients diagnosed as malignant tumor by pathology were selected as research objects by convenience sampling method, and questionnaires were conducted by using baseline data questionnaire, Chinese version of disease uncertainty scale (MUIS-A), and PTSD screening scale(PCL-C). Results: The total score of MUIS-A and PCL-C in malignant tumor patients were （90.75±11.64） and （43.04±12.12）, respectively. The total score of disease uncertainty was positively correlated with the total score of PTSD, the dimension of avoidance/numbnessand high vigilance(P<0.05), while there was no statistically significant correlation with the re-experience dimension (P>0.05). Conclusion: The patients with malignant tumors have higher levels of disease uncertainty and PTSD, and the two are positively correlated. In clinical work, patients can be provided with disease-related information to reduce their sense of uncertainty and psychological distress, such as PTSD, and ultimately improve their quality of life.