糖尿病骨质疏松发病机制的研究进展

糖尿病性骨质疏松是指以高血糖和骨密度减低为特点的内分泌代谢性疾病。在众多糖尿病并发症中,骨质疏松因其易致病理性骨折、致残致死率高等原因日益受到重视。糖尿病骨质疏松的病因复杂,包括高血糖、胰岛素绝对或相对缺乏、体质量指数、微循环异常以及降糖药物等。现就糖尿病骨质疏松发病机制的最新研究进展予以综述,为从根本上防治糖尿病患者的骨质疏松提供依据。

Research Progress of the Pathogenesis of Diabetes Osteoporosis

Diabetes-osteoporosis is a kind of endocrine metabolic disease characterized by high blood glucose and losing of the bone mineral densityAmong the many complications of diabetes,osteoporosis is drawing more and more attention because it's easy to result in pathological fracture with high disability and fatality rate.Complex factors including high blood glucose,absolute or relative lack of the insulin,BMI,microcirculation abnormality and oral glucose-lowering drugs,etc.have contributed to the etiology of disease.Here is to make a review on the latest research progress of diabetes-osteoporosis′ pathogenesis to provide references for the prevention and treatment of osteoporosis in diabetic patients.