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Localized Bullous Pemphigoid Following Orthopedic Surgery
Authors:Nima Milani-Nejad  Polina Rzepka  Matthew J Zirwas  Jessica Kaffenberger
Institution:Drs. Milani-Nejad, Rzepka, and Zirwas are with the Division of Dermatology in the Department of Internal Medicine at The Ohio State University Wexner Medical Center in Columbus, Ohio.;Dr. Kaffenberger is with The Ohio University College of Medicine in Columbus, Ohio.
Abstract:Bullous pemphigoid is an autoimmune condition whereby the immune system forms antibodies that target the skin, resulting in the formation of blisters in a generalized and symmetric pattern. Localized bullous pemphigoid can occur in special circumstances. Here, we describe two patients that developed localized bullous pemphigoid in one lower extremity following orthopedic surgery. We propose that underlying edema following orthopedic surgery is a potential trigger for localized bullous pemphigoid.
Keywords:Bullous pemphigoid  autoimmune disorder  blistering disorder  orthopedic surgery
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