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Long-term outcome of endovascular therapy for acute basilar artery occlusion
Authors:Longfei Wu  Da Zhang  Jian Chen  Chenghe Sun  Kangxiang Ji  Weili Li  Wenbo Zhao  Chuanhui Li  Chuanjie Wu  Ming Li  Di Wu  Xunming Ji
Affiliation:1.Department of Neurology and China-America Institute of Neuroscience, Capital Medical University, Beijing, China;2.Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA, USA;3.Department of Neurosurgery, Capital Medical University, Beijing, China;4.Department of Emergency, Capital Medical University, Beijing, China
Abstract:The long-term functional outcome of acute basilar artery occlusion (BAO) patients who received modern endovascular therapy (EVT) is unclear. We sought to assess the long-term functional outcome of BAO patients treated with EVT and determine the prognostic factors associated with favorable outcome. We enrolled consecutive BAO patients who received EVT between December 2012 and December 2018 in this observational study. Baseline characteristics and outcomes were presented. Multivariable logistic regression analysis was performed to identify the prognostic factors associated with long-term outcome. Among the 177 BAO patients included in this study, 80 patients (45.2%) obtained favorable outcome and 97 patients (54.8%) had unfavorable outcome at long-term follow-up with a median observation time of 12 months (interquartile range, 3–19). A total of 67 patients (37.9%) died. National Institutes of Health Stroke Scale (NIHSS), posterior circulation Alberta Stroke Program Early Computed Tomography Score (pc-ASPECTS), time from stroke onset to recanalization, and recanalization condition were identified as independent predictors for long-term outcome. Over 40% of BAO patients who were treated with modern EVT achieved favorable outcome at long-term follow-up. NIHSS, pc-ASPECTS, time from stroke onset to recanalization, and recanalization condition were identified as independent prognostic factors of long-term outcome.
Keywords:Basilar artery occlusion   endovascular therapy   long-term outcome   prognostic factor   stroke
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