| 牛乳铁蛋白稳定性研究 |
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| 引用本文： | 许宁,姚京忠,徐文斌.牛乳铁蛋白稳定性研究[J].中国药房,2005,16(3):215-216. |
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| 作者姓名： | 许宁 姚京忠 徐文斌 |
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| 作者单位： | 浙江省衢州市人民医院药剂科,衢州市,324000 |
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| 摘 要： | 目的 :研究牛乳铁蛋白原料的稳定性。方法 :以反相高效液相色谱法测定牛乳铁蛋白及其杂蛋白的含量 ,分别用强光照射法、加速试验法和室温留样观察法对牛乳铁蛋白原料进行稳定性试验。结果 :牛乳铁蛋白检测浓度线性范围为25～1000μg/ml,RSD=0 .05 % ;其在强光照射、加速试验和室温留样观察试验中 ,各项指标均符合质量标准。结论 :牛乳铁蛋白在室温、密闭的贮存条件下性质稳定。
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| 关 键 词： | 牛乳铁蛋白 杂蛋白 含量 反相高效液相色谱法 稳定性 |
| 文章编号： | 1001-0408(2005)03-0215-02 |
| 修稿时间： | 2004年7月15日 |
Study on the Stability of Bovine Lactoferrin |
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| XU Ning,YAO Jingzhong,XU Wenbin.Study on the Stability of Bovine Lactoferrin[J].China Pharmacy,2005,16(3):215-216. |
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| Authors: | XU Ning YAO Jingzhong XU Wenbin |
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| Abstract: | OBJECTIVE:To study the stability of Bovine Lactoferrin.METHODS:The content of Bovine Lactoferrin and its hybridprotein were determined by RP-HPLC.The stability of the samples was tested by high-light exposure,accelerating experiment and room temperature storage observation method.RESULTS:The linear range for Bovine Lactoferrin was25～ 1000μg/ml,RSD=0.05%.Under the high-light exposure experiment,accelerating experiment and room temperature storage observation,all the criteria were found to be in line with the quality standard specification.CONCLUSION:Stored under room temperature and airtight condition,Bovine Lactoferrin is stable in quality. |
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| Keywords: | Bovine Lactoferrin hybridprotein Content RP-HPLC Stability |
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