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深圳市南山区健康人群百日咳、白喉、破伤风抗体水平监测
引用本文:严燚,康安华,戴传文.深圳市南山区健康人群百日咳、白喉、破伤风抗体水平监测[J].实用预防医学,2007,14(5):1437-1438.
作者姓名:严燚  康安华  戴传文
作者单位:深圳市南山区疾病预防控制中心,广东,深圳,518054
摘    要:目的了解健康人群百日咳、白喉和破伤风的免疫状况。方法随机抽查部分1~40岁健康人群进行百日咳、白喉和破伤风的抗体水平监测。结果百日咳抗体几何平均滴度1:77.63,抗体保护率21.97%;白喉、破伤风抗毒素平均滴度1.33IU/ml和0.73IU/ml,阳性率99.08%和81.92%。结论对百日咳、白喉和破伤风已经形成了较好的免疫屏障,但人群百日咳抗体水平偏低,应大力推广百白破联合疫苗。

关 键 词:抗体水平  百日咳  白喉  破伤风
文章编号:1006-3110(2007)05-1437-02
收稿时间:2007-05-21
修稿时间:2007年5月21日

Surveillance on Antibody Levels of Pertussis, Diphtheria and Tetanus in Healthy Poputation of Nanshan District, Shenzhen City
YAN Yi,KANG An-hua,DAI Chuan-wen.Surveillance on Antibody Levels of Pertussis, Diphtheria and Tetanus in Healthy Poputation of Nanshan District, Shenzhen City[J].Practical Preventive Medicine,2007,14(5):1437-1438.
Authors:YAN Yi  KANG An-hua  DAI Chuan-wen
Institution:Nanshan District Center for Disease Control and Prevention, Shenzhen 518054, Guangdong, China
Abstract:Objective To understand the status of immunization against pertussis, diphtheria and tetanus in healthy poputation of Nanshan District, Shenzhen City. Methods A number of healthy persons aged between 1 and 40 were randomly selected to receive serum antibody levels monitoring investigation of pertussis, diphtheria and tetanus. Results The geometric mean titer(GMT) and rate of protection for pertussis were 1:77.63 and 21.97%. GMT of diphtheria and tetanus was 1.33 IU/ml and 0.73 IU/ml, with a positive rate of 99.08% and 81.92% respectively. Conclusion A good immunological barrier against pertussis, diphtheria and tetanus has formed, but the antibody level of pertussis is a little lower, therefore we should strongly recommend the use of adsorbed diphthreia, tetanus and acellular pertussis combined vaccine.
Keywords:Antibody levels  Pertussis  Diphtheria  Tetanus
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