| 注射用双黄连冻干粉化学成分的分离与鉴别 |
| |
| 引用本文： | 吕本强,邢学锋,罗佳波. 注射用双黄连冻干粉化学成分的分离与鉴别[J]. 南方医科大学学报, 2006, 26(10): 1471-1472,1475 |
| |
| 作者姓名： | 吕本强 邢学锋 罗佳波 |
| |
| 作者单位： | 南方医科大学中医药学院中药新药重点实验室,广东,广州,510515;中国人民解放军第421医院药剂科,广东,广州,510310;南方医科大学中医药学院中药新药重点实验室,广东,广州,510515 |
| |
| 摘 要： | 目的 究注射用双黄连粉针剂药效物质基础，为双黄连粉针剂更合理的应用和更广泛的开发提供依据。方法 用各种柱色谱方法对其化学成分进行分离，并利用各种理化、光谱技术鉴定所分离得到的化学成分。结果 双黄连粉针剂中分离得到7个化合物，经鉴定分别为：绿原酸、咖啡酸、大黄酚、大黄素甲醚、芦丁、黄芩苷和葡萄糖。结论 绿原酸、咖啡酸和黄芩苷外，其他4种化合物均系从该制剂中首次分得。
|
| 关 键 词： | 注射用双黄连粉针 化学成分 分离与鉴定 |
| 文章编号： | 1673-4254（2006）10-1471-03 |
| 收稿时间： | 2006-01-25 |
| 修稿时间： | 2006-01-25 |
Isolation of the chemical constituents from Shuanghuanglian injection and their structural identification |
| |
| L Ben-qiang,XING Xue-feng,LUO Jia-bo. Isolation of the chemical constituents from Shuanghuanglian injection and their structural identification[J]. Journal of Southern Medical University, 2006, 26(10): 1471-1472,1475 |
| |
| Authors: | L Ben-qiang XING Xue-feng LUO Jia-bo |
| |
| Affiliation: | Key New Drug Research Lab, College of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, China. lbq421@163.com |
| |
| Abstract: | OBJECTIVE: To isolate and identify the chemical constituents of Shuanghuanglian injection. METHODS: Chromatography and spectral analysis were performed to isolate and identify the chemical constituents respectively. RESULTS AND CONCLUSION: Seven compounds were isolated from Shuanghuanglian injection, including chlorogenic acid (I), caffeic acid (II), chrysophanol (III), physcion (IV), rutin (V), baicalein (VI) and glucose (VII). The compounds III, IV, V and VII were isolated and identified in Shuanghuanglian injection for the first time. |
| |
| Keywords: | Shuanghuanglian injection chemical constituents isolation and identification |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
