补肾强督祛风通络法治疗强直性脊柱炎临床疗效观察

目的：观察补肾强督祛风通络法治疗早中期强直性脊柱炎的临床疗效。方法：将100例强直性脊柱炎患者随机分为治疗组和对照组各50例，治疗组采用中药内服外敷治疗，对照组口服柳氮磺胺吡啶治疗，2纽均治疗3个月后观察临床总疗效，治疗前后中医症状积分与患者功能指数（BASFI）、病情活动指数（BASDAI）以及体征、ESR、CRP变化情况。结果：有效率治疗组为90．00％，对照组为80．00％，2组比较差异有统计学意义（P〈0．05）；治疗组治疗后中医症状积分，BASDAI、BASFI评分，中轴关节压痛指数，晨僵时间，Schober试验，指地距，脊柱活动度以及ESR、CRP等指标与治疗前比较差异均有统计学意义（P〈0．05），与对照组比较，差异有统计学意义（P〈0．05）；治疗组不良反应明显少于对照组。结论：补’肾强督祛风通络法治疗早中期强直性脊柱炎疗效肯定，安全无副作用。

Clinical Observation on Treating Ankylosing Spondylltis with the Method of Kidney-nourishing Du-meridhn-strengthening Wind-dispelling Collaterals-dredging

Objective： To observe curative effects of kidney-nourishing Du-meridian-strengthening Wind- dispelling collaterals-dredging method in treating the patients with ankylosing spondylitis at early and medium stages. Method： All 100 patients were randomized into the treatment group and the control group. The treatment group accepted TCM for internal and external use and the control group oral salazosulfapyridine. Clinical effects, changes of CRP, ESR, body signs, symptom scales, BASFI and BASDAI were observed before and after treating for three months. Result： Effective rates of both groups were 90.00% and 80.00%, the difference had statistical meaning between both groups （P〈0.05）; the difference had statistical meaning in symptom scale, BASDAI, BASFI scale, tenderness index of axial joints, the time of morning stiffness, Schober test, mean distance, spinal mobility, clinical and experimental indexes including ESR, CRP and others, when the treatment group after treating was compared with that before treating（P〈0.05）, the difference had statistical meaning compared with the control group（P〈0.05）; adverse reactions occurred in the treatment group were less than those occured of the control group. Conclusion： The method of kidney-nourishing Du-meridian-strengthening Wind-dispelling collaterals-dredging could obtain definite effects in treating ankylosing spondylitis at early and medium stages, which is safe and without side-effects.